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10.1097/SHK.0000000000000513 http://scihub22266oqcxt.onion/10.1097/SHK.0000000000000513 C4792653!4792653!26513707     free     free     free       Shock 2016 ; 45 (4): 338-48 Nephropedia Template TP {{tp|p=26513707|t=2016. The glycocalyx and Trauma: A Review |pdf=|usr=}}{{26513707}} gab.com Text The glycocalyx and Trauma: A Review JO: Shock http://www.kidney.de/pget.php?&tw=1&pmid=26513707 #FOAvip In the United States trauma is the leading cause of mortality among those under the age of 45, claiming approximately 192,000 lives each year. Significant personal disability, lost productivity and long term healthcare needs are common and contribute 580 billion dollars in economic impact each year. Improving resuscitation strategies and the early acute care of trauma patients has the potential to reduce the pathological sequelae of combined exuberant inflammation and immune suppression that can co-exist, or occur temporally, and adversely affect outcomes. The endothelial and epithelial glycocalyx has emerged as an important participant in both inflammation and immunomodulation. Constituents of the glycocalyx have been used as biomarkers of injury severity and have the potential to be target(s) for therapeutic interventions aimed at immune modulation. In this review, we provide a contemporary understanding of the physiologic structure and function of the glycocalyx and its role in traumatic injury with a particular emphasis on lung injury. Twit Text FOAVip The glycocalyx and Trauma: A Review ????Shock http://www.kidney.de/pget.php?&tw=1&pmid=26513707 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26513707 #FOAvip English Wikipedia <ref>{{Cite pmid|26513707}}</ref> The glycocalyx and Trauma: A Review #MMPMID26513707 Chignalia AZ; Yetimakman F; Christiaans SC; Unal S; Bayrakci B; Wagener BM; Russell RT; Kerby JD; Pittet JF; Dull RO Shock 2016[Apr]; 45 (4): 338-48 PMID26513707show ga In the United States trauma is the leading cause of mortality among those under the age of 45, claiming approximately 192,000 lives each year. Significant personal disability, lost productivity and long term healthcare needs are common and contribute 580 billion dollars in economic impact each year. Improving resuscitation strategies and the early acute care of trauma patients has the potential to reduce the pathological sequelae of combined exuberant inflammation and immune suppression that can co-exist, or occur temporally, and adversely affect outcomes. The endothelial and epithelial glycocalyx has emerged as an important participant in both inflammation and immunomodulation. Constituents of the glycocalyx have been used as biomarkers of injury severity and have the potential to be target(s) for therapeutic interventions aimed at immune modulation. In this review, we provide a contemporary understanding of the physiologic structure and function of the glycocalyx and its role in traumatic injury with a particular emphasis on lung injury. äThe glycocalyx and Trauma: A Review (epmc).pdf DeepDyve Pubget Overpricing