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10.12998/wjcc.v4.i3.88 http://scihub22266oqcxt.onion/10.12998/wjcc.v4.i3.88 C4792170!4792170!26989674     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       World+J+Clin+Cases 2016 ; 4 (3): 88-93 Nephropedia Template TP {{tp|p=26989674|t=2016. Combination therapy with daclatasvir and asunaprevir for dialysis patients infected with hepatitis C virus |pdf=|usr=}}{{26989674}} gab.com Text Combination therapy with daclatasvir and asunaprevir for dialysis patients infected with hepatitis C virus JO: World J Clin Cases http://www.kidney.de/pget.php?&tw=1&pmid=26989674 #FOAvip The standard antiviral therapy for dialysis patients infected with hepatitis C virus (HCV) is (pegylated) interferon monotherapy, but its efficacy is insufficient. Oral direct-acting antiviral agents (DAAs) have recently been developed for chronic hepatitis C patients. However, some DAAs have contraindications for chronic renal failure (CRF). Daclatasvir and asunaprevir are metabolized largely in the liver and are not contraindicated in CRF. Combination therapy with daclatasvir and asunaprevir was used for 4 dialysis patients infected with genotype 1b HCV. One patient had viral breakthrough, and the 3 others had sustained virological response 12. One patient was admitted for heart failure and percutaneous coronary intervention due to concomitant ischemic disease. Heart failure was unlikely to be caused by the combination therapy, as it was probably due to water overload. The patient continued to receive the combination therapy after the remission of the heart failure. The combination therapy was well tolerated in the other patients. Twit Text FOAVip Combination therapy with daclatasvir and asunaprevir for dialysis patients infected with hepatitis C virus ????World J Clin Cases http://www.kidney.de/pget.php?&tw=1&pmid=26989674 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26989674 #FOAvip English Wikipedia <ref>{{Cite pmid|26989674}}</ref> Combination therapy with daclatasvir and asunaprevir for dialysis patients infected with hepatitis C virus #MMPMID26989674 Sato K; Yamazaki Y; Ohyama T; Kobayashi T; Horiguchi N; Kakizaki S; Kusano M; Yamada M World J Clin Cases 2016[Mar]; 4 (3): 88-93 PMID26989674show ga The standard antiviral therapy for dialysis patients infected with hepatitis C virus (HCV) is (pegylated) interferon monotherapy, but its efficacy is insufficient. Oral direct-acting antiviral agents (DAAs) have recently been developed for chronic hepatitis C patients. However, some DAAs have contraindications for chronic renal failure (CRF). Daclatasvir and asunaprevir are metabolized largely in the liver and are not contraindicated in CRF. Combination therapy with daclatasvir and asunaprevir was used for 4 dialysis patients infected with genotype 1b HCV. One patient had viral breakthrough, and the 3 others had sustained virological response 12. One patient was admitted for heart failure and percutaneous coronary intervention due to concomitant ischemic disease. Heart failure was unlikely to be caused by the combination therapy, as it was probably due to water overload. The patient continued to receive the combination therapy after the remission of the heart failure. The combination therapy was well tolerated in the other patients. äCombination therapy with daclatasvir and asunaprevir for dialysis pati(epmc).pdf DeepDyve Pubget Overpricing