Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26686677
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Metab+Brain+Dis
2016 ; 31
(2
): 405-15
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Optical coherence tomography and electrophysiology of retinal and visual pathways
in Wilson s disease
#MMPMID26686677
Langwi?ska-Wo?ko E
; Litwin T
; Szulborski K
; Cz?onkowska A
Metab Brain Dis
2016[Apr]; 31
(2
): 405-15
PMID26686677
show ga
We evaluated correlations between positive findings of changes on brain magnetic
resonance imaging (MRI) and selected morphological and electrophysiological
parameters of the retinal and visual systems in Wilson's disease. Fifty-eight
Wilson's disease symptomatic patients were divided according to whether they
displayed brain changes on MRI (positive, n = 39; negative, n = 19). All
participants and healthy control group (n = 30), underwent retinal optical
coherence tomography to assess the thickness of macula and the total retinal
nerve fiber layer. Visual evoked potentials were measured and electroretinography
was performed. Macular and retinal nerve fibers were thinner in participants with
changes on MRI than in participants without changes. Electrophysiological
parameters were markedly different in the MRI positive group compared with the
negative group and 30 healthy controls; however, some abnormalities were evident
in cases without visible brain pathology. Morphological and electrophysiological
changes of retinal and visual pathways are associated with MRI visualized brain
injury in Wilson's disease and may be useful for detecting the degree of
neurodegeneration.