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10.5483/BMBRep.2015.48.12.215 http://scihub22266oqcxt.onion/10.5483/BMBRep.2015.48.12.215 C4791322!4791322!26497581     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       BMB+Rep 2015 ; 48 (12): 668-76 Nephropedia Template TP {{tp|p=26497581|t=2015. Stem cell maintenance by manipulating signaling pathways: past, current and future |pdf=|usr=}}{{26497581}} gab.com Text Stem cell maintenance by manipulating signaling pathways: past, current and future JO: BMB Rep http://www.kidney.de/pget.php?&tw=1&pmid=26497581 #FOAvip Pluripotent stem cells only exist in a narrow window during early embryonic development, whereas multipotent stem cells are abundant throughout embryonic development and are retainedin various adult tissues and organs. While pluripotent stem cell lines have been established from several species, including mouse, rat, and human, it is still challenging to establish stable multipotent stem cell lines from embryonic or adult tissues. Based on current knowledge, we anticipate that by manipulating extrinsic and intrinsic signaling pathways, most if not all types of stem cells can be maintained in a long-term culture. In this article, we summarize current culture conditions established for the long-term maintenance of authentic pluripotent and multipotent stem cells and the signaling pathways involved. We also discuss the general principles of stem cell maintenance and propose several strategies on the establishment of novel stem cell lines through manipulation of signaling pathways. [BMB Reports 2015; 48(12): 668-676] Twit Text FOAVip Stem cell maintenance by manipulating signaling pathways: past, current and future ????BMB Rep http://www.kidney.de/pget.php?&tw=1&pmid=26497581 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26497581 #FOAvip English Wikipedia <ref>{{Cite pmid|26497581}}</ref> Stem cell maintenance by manipulating signaling pathways: past, current and future #MMPMID26497581 Chen X; Ye S; Ying QL BMB Rep 2015[Dec]; 48 (12): 668-76 PMID26497581show ga Pluripotent stem cells only exist in a narrow window during early embryonic development, whereas multipotent stem cells are abundant throughout embryonic development and are retainedin various adult tissues and organs. While pluripotent stem cell lines have been established from several species, including mouse, rat, and human, it is still challenging to establish stable multipotent stem cell lines from embryonic or adult tissues. Based on current knowledge, we anticipate that by manipulating extrinsic and intrinsic signaling pathways, most if not all types of stem cells can be maintained in a long-term culture. In this article, we summarize current culture conditions established for the long-term maintenance of authentic pluripotent and multipotent stem cells and the signaling pathways involved. We also discuss the general principles of stem cell maintenance and propose several strategies on the establishment of novel stem cell lines through manipulation of signaling pathways. [BMB Reports 2015; 48(12): 668-676] äStem cell maintenance by manipulating signaling pathways: past, curren(epmc).pdf DeepDyve Pubget Overpricing