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10.1073/pnas.1519210113 http://scihub22266oqcxt.onion/10.1073/pnas.1519210113 C4790994!4790994!26929366     free     free     free Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2016 ; 113 (10): 2672-7 Nephropedia Template TP {{tp|p=26929366|t=2016. Dynamics inside the cancer cell attractor reveal cell heterogeneity, limits of stability, and escape |pdf=|usr=}}{{26929366}} gab.com Text Dynamics inside the cancer cell attractor reveal cell heterogeneity, limits of stability, and escape JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=26929366 #FOAvip It has been proposed, based on theory of complex gene regulatory networks, that cell types, including cancer cells, represent attractor states of the network dynamics. Here, we characterize for the first time, to our knowledge, the detailed dynamics of a cancer cell attractor at single-cell resolution. The results provide quantitative knowledge on nongenetic intercellular heterogeneity and its dynamics within an isogenic cell population of cancerous cells, affording insights at a previously unidentified level of resolution between molecular pathways and macroscopic tumor behaviors. This new dimension of characterizing tumor cells might impact design of future rational cancer therapies by taking into account the dynamic robustness and high volatility of a heterogeneous cancer cell population. Twit Text FOAVip Dynamics inside the cancer cell attractor reveal cell heterogeneity, limits of stability, and escape ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=26929366 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26929366 #FOAvip English Wikipedia <ref>{{Cite pmid|26929366}}</ref> Dynamics inside the cancer cell attractor reveal cell heterogeneity, limits of stability, and escape #MMPMID26929366 Li Q; Wennborg A; Aurell E; Dekel E; Zou JZ; Xu Y; Huang S; Ernberg I Proc Natl Acad Sci U S A 2016[Mar]; 113 (10): 2672-7 PMID26929366show ga It has been proposed, based on theory of complex gene regulatory networks, that cell types, including cancer cells, represent attractor states of the network dynamics. Here, we characterize for the first time, to our knowledge, the detailed dynamics of a cancer cell attractor at single-cell resolution. The results provide quantitative knowledge on nongenetic intercellular heterogeneity and its dynamics within an isogenic cell population of cancerous cells, affording insights at a previously unidentified level of resolution between molecular pathways and macroscopic tumor behaviors. This new dimension of characterizing tumor cells might impact design of future rational cancer therapies by taking into account the dynamic robustness and high volatility of a heterogeneous cancer cell population. äDynamics inside the cancer cell attractor reveal cell heterogeneity, l(epmc).pdf DeepDyve Pubget Overpricing