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2016 ; 62
(2
): 203-10
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"Treating Lungs": The Scientific Contributions of Dr Theodor Kolobow
#MMPMID26720733
Trahanas JM
; Kolobow MA
; Hardy MA
; Berra L
; Zapol WM
; Bartlett RH
ASAIO J
2016[Mar]; 62
(2
): 203-10
PMID26720733
show ga
We are fortunate to live in an age in which biomedical technology has provided us
with unprecedented ability to supplant the functions of organs and support the
physiologic processes of the human body. Ingenious doctors, physiologists, and
engineers helped create these advances with new and innovative ideas. One of
these pioneers was Dr. Theodor Kolobow. He is best known for one of his earliest
inventions, the spiral coil membrane lung. His contributions to medical
innovation, however, are diverse, as he also contributed to advances in
hemodialysis, improvements in extracorporeal life support technology/circuit
components, and through his laboratory experiments helped shape our current
understanding of cardiopulmonary pathophysiology. In retrospect, much of
Kolobow's work was unified by the theme of preventing iatrogenic lung injury
caused by mechanical ventilation. This tenet became more obvious as his later
studies progressed to developing techniques and devices intended to limit
ventilator pressures, and prevent bacterial colonization of the lungs. Although
he formally retired from his research endeavors in 2009, the impact of his
contributions remains prominent in our everyday use of techniques and equipment
that he either originated or helped to develop.