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10.3390/antibiotics4030337 http://scihub22266oqcxt.onion/10.3390/antibiotics4030337 C4790290!4790290!27025628     free     free     free Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Antibiotics+(Basel) 2015 ; 4 (3): 337-57 Nephropedia Template TP {{tp|p=27025628|t=2015. Colonization Resistance of the Gut Microbiota against Clostridium difficile |pdf=|usr=}}{{27025628}} gab.com Text Colonization Resistance of the Gut Microbiota against Clostridium difficile JO: Antibiotics (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=27025628 #FOAvip Antibiotics strongly disrupt the human gut microbiota, which in consequence loses its colonization resistance capacity, allowing infection by opportunistic pathogens such as Clostridium difficile. This bacterium is the main cause of antibiotic-associated diarrhea and a current problem in developed countries, since its incidence and severity have increased during the last years. Furthermore, the emergence of antibiotic resistance strains has reduced the efficiency of the standard treatment with antibiotics, leading to a higher rate of relapses. Here, we review recent efforts focused on the impact of antibiotics in the gut microbiome and their relationship with C. difficile colonization, as well as, in the identification of bacteria and mechanisms involved in the protection against C. difficile infection. Since a healthy gut microbiota is able to avoid pathogen colonization, restoration of the gut microbiota seems to be the most promising approach to face C. difficile infection, especially for recurrent cases. Therefore, it would be possible to design probiotics for patients undergoing antimicrobial therapies in order to prevent or fight the expansion of the pathogen in the gut ecosystem. Twit Text FOAVip Colonization Resistance of the Gut Microbiota against Clostridium difficile ????Antibiotics (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=27025628 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27025628 #FOAvip English Wikipedia <ref>{{Cite pmid|27025628}}</ref> Colonization Resistance of the Gut Microbiota against Clostridium difficile #MMPMID27025628 Pérez-Cobas AE; Moya A; Gosalbes MJ; Latorre A Antibiotics (Basel) 2015[Sep]; 4 (3): 337-57 PMID27025628show ga Antibiotics strongly disrupt the human gut microbiota, which in consequence loses its colonization resistance capacity, allowing infection by opportunistic pathogens such as Clostridium difficile. This bacterium is the main cause of antibiotic-associated diarrhea and a current problem in developed countries, since its incidence and severity have increased during the last years. Furthermore, the emergence of antibiotic resistance strains has reduced the efficiency of the standard treatment with antibiotics, leading to a higher rate of relapses. Here, we review recent efforts focused on the impact of antibiotics in the gut microbiome and their relationship with C. difficile colonization, as well as, in the identification of bacteria and mechanisms involved in the protection against C. difficile infection. Since a healthy gut microbiota is able to avoid pathogen colonization, restoration of the gut microbiota seems to be the most promising approach to face C. difficile infection, especially for recurrent cases. Therefore, it would be possible to design probiotics for patients undergoing antimicrobial therapies in order to prevent or fight the expansion of the pathogen in the gut ecosystem. äColonization Resistance of the Gut Microbiota against Clostridium diff(epmc).pdf DeepDyve Pubget Overpricing