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Effect of Pneumoperitoneum on Renal Function and Physiology in Patients
Undergoing Robotic Renal Surgery
#MMPMID26989363
Sodha S
; Nazarian S
; Adshead JM
; Vasdev N
; Mohan-S G
Curr Urol
2016[Feb]; 9
(1
): 1-4
PMID26989363
show ga
Laparoscopic and minimally-invasive robotic access has transformed the delivery
of urological surgery. While associated with numerous desirable outcomes
including shorter post-operative stay and faster return to preoperative function,
these techniques have also been associated with increased morbidity such as
reduced renal blood flow and post-operative renal dysfunction. The mechanisms
leading to these renal effects complex and multifactorial, and have not been
fully elucidated. However they are likely to include direct effects from raised
intra-abdominal pressure, and indirect effects secondary to carbon dioxide
absorption, neuroendocrine factors and tissue damage from oxidative stress. This
review summarises these factors, and highlights the need for further work in this
area, to direct novel therapies and guide alterations in technique with the aim
of reducing renal dysfunction post-laparoscopic and robotic surgery.
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