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Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Sci+Rep 2016 ; 6 (ä): ä Nephropedia Template TP
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Bacteriophage application to control the contaminated water with Shigella #MMPMID26971572
Jun JW; Giri SS; Kim HJ; Yun SK; Chi C; Chai JY; Lee BC; Park SC
Sci Rep 2016[]; 6 (ä): ä PMID26971572show ga
Shigella is one of the most important waterborne and foodborne pathogens around the world. Emergence of antibiotic-resistant Shigella has made the development of alternatives to conventional antibiotics necessary. In this study, a virulent Myoviridae bacteriophage, pSs-1 was isolated from environmental water in South Korea and showed infectivity to S. flexneri as well as S. sonnei strains. One-step growth analysis showed that pSs-1 has a short latent period (25?min) and a large burst size (97?PFU/cell). According to the genomic analysis, pSs-1 contains 164,999?bp of genome with a G?+?C content of 35.54% and it is considered as a member of the T4-like bacteriophage group. These results showed that pSs-1 may have potential as a biocontrol agent instead of conventional antibiotics for shigellosis.