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10.3389/fmicb.2016.00313

http://scihub22266oqcxt.onion/10.3389/fmicb.2016.00313
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C4789553!4789553!27014235
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suck abstract from ncbi


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pmid27014235      Front+Microbiol 2016 ; 7 (ä): ä
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  • Cytosolic Innate Immune Sensing and Signaling upon Infection #MMPMID27014235
  • Radoshevich L; Dussurget O
  • Front Microbiol 2016[]; 7 (ä): ä PMID27014235show ga
  • Cytosolic sensing of pathogens is essential to a productive immune response. Recent reports have emphasized the importance of signaling platforms emanating from organelles and cytosolic sensors, particularly during the response to intracellular pathogens. Here, we highlight recent discoveries identifying the key mediators of nucleic acid and cyclic nucleotide sensing and discuss their importance in host defense. This review will also cover strategies evolved by pathogens to manipulate these pathways.
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