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10.2217/fon.13.30

http://scihub22266oqcxt.onion/10.2217/fon.13.30
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C4788699!4788699!23718302
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suck abstract from ncbi


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pmid23718302      Future+Oncol 2013 ; ä (ä): 817-24
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  • Translation of the ecological trap concept to glioma therapy: the cancer cell trap concept #MMPMID23718302
  • Van Der Sanden B; Appaix F; Berger F; Selek L; Issartel JP; Wion D
  • Future Oncol 2013[]; ä (ä): 817-24 PMID23718302show ga
  • Viewing tumors as ecosystems offers the opportunity to consider how ecological concepts can be translated to novel therapeutic perspectives. The ecological trap concept emerged about half a century ago when it was observed that animals can prefer environment of low quality for survival over other available of higher quality. The presence of such a trap can drive a local population to extinction. The cancer cell trap concept is the translation of the ecological trap into glioma therapy. It exploits and diverts the invasive potential of glioma cells to guide their migration towards specific locations where a local therapy can be delivered efficiently. This illustrates how an ecological concept can change therapeutic obstacles into therapeutic tools.
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