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10.1128/CMR.00069-15 http://scihub22266oqcxt.onion/10.1128/CMR.00069-15 C4786882!4786882 !26960941     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26960941 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Clin+Microbiol+Rev 2016 ; 29 (2 ): 401-27 Nephropedia Template TP {{tp|p=26960941 |t=2016. Clinical Significance and Pathogenesis of Staphylococcal Small Colony Variants in Persistent Infections |pdf=|usr=}}{{26960941 }} gab.com Text Clinical Significance and Pathogenesis of Staphylococcal Small Colony Variants in Persistent Infections JO: Clin Microbiol Rev http://www.kidney.de/pget.php?&tw=1&pmid=26960941 #FOAvip Small colony variants (SCVs) were first described more than 100 years ago for Staphylococcus aureus and various coagulase-negative staphylococci. Two decades ago, an association between chronic staphylococcal infections and the presence of SCVs was observed. Since then, many clinical studies and observations have been published which tie recurrent, persistent staphylococcal infections, including device-associated infections, bone and tissue infections, and airway infections of cystic fibrosis patients, to this special phenotype. By their intracellular lifestyle, SCVs exhibit so-called phenotypic (or functional) resistance beyond the classical resistance mechanisms, and they can often be retrieved from therapy-refractory courses of infection. In this review, the various clinical infections where SCVs can be expected and isolated, diagnostic procedures for optimized species confirmation, and the pathogenesis of SCVs, including defined underlying molecular mechanisms and the phenotype switch phenomenon, are presented. Moreover, relevant animal models and suggested treatment regimens, as well as the requirements for future research areas, are highlighted. Twit Text FOAVip Clinical Significance and Pathogenesis of Staphylococcal Small Colony Variants in Persistent Infections ????Clin Microbiol Rev http://www.kidney.de/pget.php?&tw=1&pmid=26960941 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26960941 #FOAvip English Wikipedia <ref>{{Cite pmid|26960941 }}</ref> Clinical Significance and Pathogenesis of Staphylococcal Small Colony Variants in Persistent Infections #MMPMID26960941 Kahl BC ; Becker K ; Löffler B Clin Microbiol Rev 2016[Apr]; 29 (2 ): 401-27 PMID26960941 show ga Small colony variants (SCVs) were first described more than 100 years ago for Staphylococcus aureus and various coagulase-negative staphylococci. Two decades ago, an association between chronic staphylococcal infections and the presence of SCVs was observed. Since then, many clinical studies and observations have been published which tie recurrent, persistent staphylococcal infections, including device-associated infections, bone and tissue infections, and airway infections of cystic fibrosis patients, to this special phenotype. By their intracellular lifestyle, SCVs exhibit so-called phenotypic (or functional) resistance beyond the classical resistance mechanisms, and they can often be retrieved from therapy-refractory courses of infection. In this review, the various clinical infections where SCVs can be expected and isolated, diagnostic procedures for optimized species confirmation, and the pathogenesis of SCVs, including defined underlying molecular mechanisms and the phenotype switch phenomenon, are presented. Moreover, relevant animal models and suggested treatment regimens, as well as the requirements for future research areas, are highlighted. |Animals [MESH] |Bacterial Typing Techniques [MESH] |Cross Infection/microbiology [MESH] |Disease Models, Animal [MESH] |Humans [MESH] |Phenotype [MESH] |Staphylococcal Infections/*diagnosis/pathology/*transmission [MESH]Clinical Significance and Pathogenesis of Staphylococcal Small Colony (epmc).pdf DeepDyve Pubget Overpricing