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10.1016/j.juro.2013.08.024 http://scihub22266oqcxt.onion/10.1016/j.juro.2013.08.024 C4786018!4786018!23973521     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=23973521&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Urol 2014 ; 191 (2): 364-70 Nephropedia Template TP {{tp|p=23973521|t=2014. An Endogenous Pain Control System Is Altered In Subjects With Interstitial Cystitis |pdf=|usr=}}{{23973521}} gab.com Text An Endogenous Pain Control System Is Altered In Subjects With Interstitial Cystitis JO: J Urol http://www.kidney.de/pget.php?&tw=1&pmid=23973521 #FOAvip Purpose: Multiple studies have demonstrated that in healthy subjects painful stimuli applied to one part of the body inhibit pain sensation in other parts of the body, a phenomenon referred to as conditioned pain modulation (CPM). CPM is related to the presence of endogenous pain control systems. Studies have demonstrated deficits in CPM-associated inhibition in many, but not all chronic pain disorders. The present study sought to determine whether CPM was altered in subjects with Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS). Methods and Materials: Female subjects with and without the diagnosis of IC/BPS were studied psychophysically using quantitative cutaneous thermal, forearm ischemia and ice water immersion tests. CPM was assessed by quantifying the effects of immersion of the hand in ice water (conditioning stimulus) on threshold and tolerance of cutaneous heat pain (test stimulus) applied to the contralateral lower extremity. Results: CPM responses of the subjects with IC/BPS were statistically different from those of healthy control subjects for both cutaneous thermal threshold and tolerance measures. Healthy control subjects demonstrated statistically significant increases in their thermal pain tolerances whereas subjects with the diagnosis of IC/BPS demonstrated statistically significant reductions in their thermal pain tolerances. Conclusions: An endogenous pain inhibitory system normally observed with CPM was altered in subjects with IC/BPS. This identifies IC/BPS as similar to several other chronic pain disorders such as fibromyalgia and irritable bowel syndrome and suggests that a deficit in endogenous pain inhibitory systems may be a contributor to such chronic pain disorders. Twit Text FOAVip An Endogenous Pain Control System Is Altered In Subjects With Interstitial Cystitis ????J Urol http://www.kidney.de/pget.php?&tw=1&pmid=23973521 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23973521 #FOAvip English Wikipedia <ref>{{Cite pmid|23973521}}</ref> An Endogenous Pain Control System Is Altered In Subjects With Interstitial Cystitis #MMPMID23973521 Ness TJ; Lloyd LK; Fillingim RB J Urol 2014[Feb]; 191 (2): 364-70 PMID23973521show ga Purpose: Multiple studies have demonstrated that in healthy subjects painful stimuli applied to one part of the body inhibit pain sensation in other parts of the body, a phenomenon referred to as conditioned pain modulation (CPM). CPM is related to the presence of endogenous pain control systems. Studies have demonstrated deficits in CPM-associated inhibition in many, but not all chronic pain disorders. The present study sought to determine whether CPM was altered in subjects with Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS). Methods and Materials: Female subjects with and without the diagnosis of IC/BPS were studied psychophysically using quantitative cutaneous thermal, forearm ischemia and ice water immersion tests. CPM was assessed by quantifying the effects of immersion of the hand in ice water (conditioning stimulus) on threshold and tolerance of cutaneous heat pain (test stimulus) applied to the contralateral lower extremity. Results: CPM responses of the subjects with IC/BPS were statistically different from those of healthy control subjects for both cutaneous thermal threshold and tolerance measures. Healthy control subjects demonstrated statistically significant increases in their thermal pain tolerances whereas subjects with the diagnosis of IC/BPS demonstrated statistically significant reductions in their thermal pain tolerances. Conclusions: An endogenous pain inhibitory system normally observed with CPM was altered in subjects with IC/BPS. This identifies IC/BPS as similar to several other chronic pain disorders such as fibromyalgia and irritable bowel syndrome and suggests that a deficit in endogenous pain inhibitory systems may be a contributor to such chronic pain disorders. äAn Endogenous Pain Control System Is Altered In Subjects With Intersti(epmc).pdf DeepDyve Pubget Overpricing