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10.1097/HRP.0000000000000110 http://scihub22266oqcxt.onion/10.1097/HRP.0000000000000110 C4785844!4785844!26954597     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Harv+Rev+Psychiatry 2016 ; 24 (2): 129-47 Nephropedia Template TP {{tp|p=26954597|t=2016. Electrophysiological Endophenotypes for Schizophrenia |pdf=|usr=}}{{26954597}} gab.com Text Electrophysiological Endophenotypes for Schizophrenia JO: Harv Rev Psychiatry http://www.kidney.de/pget.php?&tw=1&pmid=26954597 #FOAvip Endophenotypes are quantitative, heritable traits that may help to elucidate the pathophysiologic mechanisms underlying complex disease syndromes, such as schizophrenia. They can be assessed at numerous levels of analysis; here, we review electrophysiological endophenotypes that have shown promise in helping us understand schizophrenia from a more mechanistic point of view. For each endophenotype, we describe typical experimental procedures, reliability, heritability, and reported gene and neurobiological associations. We discuss recent findings regarding the genetic architecture of specific electrophysiological endophenotypes, as well as converging evidence from EEG studies implicating disrupted balance of glutamatergic signaling and GABA-ergic inhibition in the pathophysiology of schizophrenia. We conclude that refining the measurement of electrophysiological endophenotypes, expanding genetic association studies, and integrating datasets are important next steps for understanding the mechanisms that connect identified genetic risk loci for schizophrenia to the disease phenotype. Twit Text FOAVip Electrophysiological Endophenotypes for Schizophrenia ????Harv Rev Psychiatry http://www.kidney.de/pget.php?&tw=1&pmid=26954597 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26954597 #FOAvip English Wikipedia <ref>{{Cite pmid|26954597}}</ref> Electrophysiological Endophenotypes for Schizophrenia #MMPMID26954597 Owens E; Bachman P; Glahn DC; Bearden CE Harv Rev Psychiatry 2016[Mar]; 24 (2): 129-47 PMID26954597show ga Endophenotypes are quantitative, heritable traits that may help to elucidate the pathophysiologic mechanisms underlying complex disease syndromes, such as schizophrenia. They can be assessed at numerous levels of analysis; here, we review electrophysiological endophenotypes that have shown promise in helping us understand schizophrenia from a more mechanistic point of view. For each endophenotype, we describe typical experimental procedures, reliability, heritability, and reported gene and neurobiological associations. We discuss recent findings regarding the genetic architecture of specific electrophysiological endophenotypes, as well as converging evidence from EEG studies implicating disrupted balance of glutamatergic signaling and GABA-ergic inhibition in the pathophysiology of schizophrenia. We conclude that refining the measurement of electrophysiological endophenotypes, expanding genetic association studies, and integrating datasets are important next steps for understanding the mechanisms that connect identified genetic risk loci for schizophrenia to the disease phenotype. äElectrophysiological Endophenotypes for Schizophrenia (epmc).pdf DeepDyve Pubget Overpricing