Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27013839
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Glob+Infect+Dis
2016 ; 8
(1
): 3-15
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
The Emergence of Zika Virus as a Global Health Security Threat: A Review and a
Consensus Statement of the INDUSEM Joint working Group (JWG)
#MMPMID27013839
J Glob Infect Dis
2016[Jan]; 8
(1
): 3-15
PMID27013839
show ga
The Zika virus (ZIKV), first discovered in 1947, has emerged as a global public
health threat over the last decade, with the accelerated geographic spread of the
virus noted during the last 5 years. The World Health Organization (WHO) predicts
that millions of cases of ZIKV are likely to occur in the Americas during the
next 12 months. These projections, in conjunction with suspected Zika-associated
increase in newborn microcephaly cases, prompted WHO to declare public health
emergency of international concern. ZIKV-associated illness is characterized by
an incubation period of 3-12 days. Most patients remain asymptomatic (i.e., ~80%)
after contracting the virus. When symptomatic, clinical presentation is usually
mild and consists of a self-limiting febrile illness that lasts approximately 2-7
days. Among common clinical manifestations are fever, arthralgia, conjunctivitis,
myalgia, headache, and maculopapular rash. Hospitalization and complication rates
are low, with fatalities being extremely rare. Newborn microcephaly, the most
devastating and insidious complication associated with the ZIKV, has been
described in the offspring of women who became infected while pregnant. Much
remains to be elucidated about the timing of ZIKV infection in the context of the
temporal progression of pregnancy, the corresponding in utero fetal development
stage(s), and the risk of microcephaly. Without further knowledge of the
pathophysiology involved, the true risk of ZIKV to the unborn remains difficult
to quantify and remediate. Accurate, portable, and inexpensive point-of-care
testing is required to better identify cases and manage the current and future
outbreaks of ZIKV, including optimization of preventive approaches and the
identification of more effective risk reduction strategies. In addition, much
more work needs to be done to produce an effective vaccine. Given the rapid
geographic spread of ZIKV in recent years, a coordinated local, regional, and
global effort is needed to generate sufficient resources and political traction
to effectively halt and contain further expansion of the current outbreak.