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Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Biochem+J 2016 ; 473 (Pt 6): 757-67 Nephropedia Template TP
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Epithelial?mesenchymal transition, IP3 receptors and ER?PM junctions: translocation of Ca2+ signalling complexes and regulation of migration #MMPMID26759379
Okeke E; Parker T; Dingsdale H; Concannon M; Awais M; Voronina S; Molgó J; Begg M; Metcalf D; Knight A; Sutton R; Haynes L; Tepikin A
Biochem J 2016[Mar]; 473 (Pt 6): 757-67 PMID26759379show ga
During epithelial?mesenchymal transition IP3Rs relocate from tight junctions to the leading edge of migrating pancreatic cancer cells and regulate dynamics of focal adhesions. STIM1-competent ER?PM junctions position closely behind IP3Rs and, together with IP3Rs, regulate cell migration.