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10.1042/BJ20150364

http://scihub22266oqcxt.onion/10.1042/BJ20150364
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C4785603!4785603!26759379
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suck abstract from ncbi


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pmid26759379      Biochem+J 2016 ; 473 (Pt 6): 757-67
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  • Epithelial?mesenchymal transition, IP3 receptors and ER?PM junctions: translocation of Ca2+ signalling complexes and regulation of migration #MMPMID26759379
  • Okeke E; Parker T; Dingsdale H; Concannon M; Awais M; Voronina S; Molgó J; Begg M; Metcalf D; Knight A; Sutton R; Haynes L; Tepikin A
  • Biochem J 2016[Mar]; 473 (Pt 6): 757-67 PMID26759379show ga
  • During epithelial?mesenchymal transition IP3Rs relocate from tight junctions to the leading edge of migrating pancreatic cancer cells and regulate dynamics of focal adhesions. STIM1-competent ER?PM junctions position closely behind IP3Rs and, together with IP3Rs, regulate cell migration.
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