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Haemostasis in Thyroid Surgery: Collagen-Fibrinogen-Thrombin Patch versus
Cellulose Gauze-Our Experience
#MMPMID27018148
Tartaglia N
; Di Lascia A
; Lizzi V
; Cianci P
; Fersini A
; Ambrosi A
; Neri V
Surg Res Pract
2016[]; 2016
(?): 3058754
PMID27018148
show ga
Purpose. Postoperative hemorrhage is fortunately uncommon but potentially
life-threatening complication of thyroid surgery that increases the postoperative
morbidity and the hospital stay. In this study we compare the efficacy of
collagen patch coated with human fibrinogen and human thrombin (CFTP) (group C)
and oxidized regenerated cellulose gauze (group B) versus traditional hemostatic
procedures (group A) in thyroid surgery. Methods. From January 2011 to December
2013, 226 were eligible for our prospective, nonrandomized, comparative study.
Patients requiring a video-assisted thyroidectomy without drain, "near total," or
hemithyroidectomy were excluded. Other exclusion criteria were a diagnosis of
malignancy, substernal goiter, disorders of hemostasis or coagulation, and Graves
or hyperfunctioning thyroid diseases. Outcomes included duration of operation,
drainage volume, and postoperative complications. Results. Our results show a
significant reduction in drainage volume in group C in comparison with the other
two groups. In group C there was no bleeding but the limited numbers do not make
this result significant. There were no differences in terms of other
complications, except for the incidence of seroma in group B. Conclusion. The use
of CFTP reduces the drainage volume, potentially the bleeding complications, and
the hospital stay. These findings confirm the efficacy of CFTP, encouraging its
use in thyroid surgery.
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