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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Acta+Crystallogr+D+Struct+Biol
2016 ; 72
(Pt 3
): 413-20
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English Wikipedia
Facilitating best practices in collecting anomalous scattering data for de novo
structure solution at the ESRF Structural Biology Beamlines
#MMPMID26960128
de Sanctis D
; Oscarsson M
; Popov A
; Svensson O
; Leonard G
Acta Crystallogr D Struct Biol
2016[Mar]; 72
(Pt 3
): 413-20
PMID26960128
show ga
The constant evolution of synchrotron structural biology beamlines, the viability
of screening protein crystals for a wide range of heavy-atom derivatives, the
advent of efficient protein labelling and the availability of automatic
data-processing and structure-solution pipelines have combined to make de novo
structure solution in macromolecular crystallography a less arduous task.
Nevertheless, the collection of diffraction data of sufficient quality for
experimental phasing is still a difficult and crucial step. Here, some examples
of good data-collection practice for projects requiring experimental phasing are
presented and recent developments at the ESRF Structural Biology beamlines that
have facilitated these are illustrated.