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10.3390/ijms17020224

http://scihub22266oqcxt.onion/10.3390/ijms17020224
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suck abstract from ncbi


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pmid26861310      Int+J+Mol+Sci 2016 ; 17 (2): ä
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  • Hepatotoxicity by Drugs: The Most Common Implicated Agents #MMPMID26861310
  • Björnsson ES
  • Int J Mol Sci 2016[Feb]; 17 (2): ä PMID26861310show ga
  • Idiosyncratic drug-induced liver injury (DILI) is an underreported and underestimated adverse drug reaction. Information on the documented hepatotoxicity of drugs has recently been made available by a website that can be accessed in the public domain: LiverTox (http://livertox.nlm.nih.gov). According to critical analysis of the hepatotoxicity of drugs in LiverTox, 53% of drugs had at least one case report of convincing reports of liver injury. Only 48 drugs had more than 50 case reports of DILI. Amoxicillin-clavulanate is the most commonly implicated agent leading to DILI in the prospective series. In a recent prospective study, liver injury due to amoxicillin-clavulanate was found to occur in approximately one out of 2300 users. Drugs with the highest risk of DILI in this study were azathioprine and infliximab.
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