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10.3390/ijms17020201

http://scihub22266oqcxt.onion/10.3390/ijms17020201
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C4783935!4783935!26861284
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suck abstract from ncbi


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pmid26861284      Int+J+Mol+Sci 2016 ; 17 (2): ä
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  • Drug-Induced Liver Injury Network Causality Assessment: Criteria and Experience in the United States #MMPMID26861284
  • Hayashi PH
  • Int J Mol Sci 2016[Feb]; 17 (2): ä PMID26861284show ga
  • Hepatotoxicity due to drugs, herbal or dietary supplements remains largely a clinical diagnosis based on meticulous history taking and exclusion of other causes of liver injury. In 2004, the U.S. Drug-Induced Liver Injury Network (DILIN) was created under the auspices of the U.S. National Institute of Diabetes and Digestive and Kidney Diseases with the aims of establishing a large registry of cases for clinical, epidemiological and mechanistic study. From inception, the DILIN has used an expert opinion process that incorporates consensus amongst three different DILIN hepatologists assigned to each case. It is the most well-established, well-described and vigorous expert opinion process for DILI to date, and yet it is an imperfect standard. This review will discuss the DILIN expert opinion process, its strengths and weaknesses, psychometric performance and future.
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