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10.3390/ijms17020173 http://scihub22266oqcxt.onion/10.3390/ijms17020173 C4783907!4783907 !26861304     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26861304 &cmd=llinks): Failed to open stream: HTTP request failed! 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Focus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer s and Parkinson s Disease |pdf=|usr=}}{{26861304 }} gab.com Text Focus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer s and Parkinson s Disease JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=26861304 #FOAvip Growing evidence indicates that small extracellular vesicles, called exosomes, are prominent mediators of neurodegenerative diseases such as prion, Alzheimer's and Parkinson's disease. Exosomes contain neurodegenerative disease associated proteins such as the prion protein, ?-amyloid and ?-synuclein. Only demonstrated so far in vivo with prion disease, exosomes are hypothesised to also facilitate the spread of ?-amyloid and ?-synuclein from their cells of origin to the extracellular environment. In the current review, we will discuss the role of exosomes in Alzheimer's and Parkinson's disease including their possible contribution to disease propagation and pathology and highlight their utility as a diagnostic in neurodegenerative disease. Twit Text FOAVip Focus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer s and Parkinson s Disease ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=26861304 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26861304 #FOAvip English Wikipedia <ref>{{Cite pmid|26861304 }}</ref> Focus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer s and Parkinson s Disease #MMPMID26861304 Vella LJ ; Hill AF ; Cheng L Int J Mol Sci 2016[Feb]; 17 (2 ): 173 PMID26861304 show ga Growing evidence indicates that small extracellular vesicles, called exosomes, are prominent mediators of neurodegenerative diseases such as prion, Alzheimer's and Parkinson's disease. Exosomes contain neurodegenerative disease associated proteins such as the prion protein, ?-amyloid and ?-synuclein. Only demonstrated so far in vivo with prion disease, exosomes are hypothesised to also facilitate the spread of ?-amyloid and ?-synuclein from their cells of origin to the extracellular environment. In the current review, we will discuss the role of exosomes in Alzheimer's and Parkinson's disease including their possible contribution to disease propagation and pathology and highlight their utility as a diagnostic in neurodegenerative disease. |Alzheimer Disease/*metabolism/therapy [MESH] |Amyloid beta-Peptides/chemistry/metabolism [MESH] |Animals [MESH] |Biomarkers [MESH] |Exosomes/*metabolism [MESH] |Extracellular Vesicles/*metabolism [MESH] |Humans [MESH] |Parkinson Disease/*metabolism/therapy [MESH] |Protein Folding [MESH] |Protein Transport [MESH]Focus on Extracellular Vesicles: Exosomes and Their Role in Protein Tr(epmc).pdf DeepDyve Pubget Overpricing