Structural insights of mTOR complex 1 #MMPMID26794870
Yuan HX; Guan KL
Cell Res 2016[Mar]; 26 (3): 267-8 PMID26794870show ga
The mammalian target of rapamycin (mTOR), also known as the mechanistic target of rapamycin, is a central cell growth regulating kinase that forms large molecular complexes in all eukaryotic cells. A paper recently published in Science reports the architecture of mTOR complex 1 (mTORC1) and provides molecular insights into the regulation and substrate selectivity of mTORC1.