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10.1016/j.tibs.2015.11.012 http://scihub22266oqcxt.onion/10.1016/j.tibs.2015.11.012 C4783254!4783254!26725301     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Trends+Biochem+Sci 2016 ; 41 (3): 274-86 Nephropedia Template TP {{tp|p=26725301|t=2016. Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease |pdf=|usr=}}{{26725301}} gab.com Text Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease JO: Trends Biochem Sci http://www.kidney.de/pget.php?&tw=1&pmid=26725301 #FOAvip Iron is necessary for life, but can also cause cell death. Accordingly, cells evolved a robust, tightly regulated suite of genes for maintaining iron homeostasis. Previous mechanistic studies on iron homeostasis have granted insight into the role of iron in human health and disease. We highlight new regulators of iron metabolism, including iron-trafficking proteins [solute carrier family 39, SLC39, also known as ZRT/IRT-like protein, ZIP; and poly-(rC)-binding protein, PCBP] and a cargo receptor (NCOA4) that is crucial for release of ferritin-bound iron. We also discuss emerging roles of iron in apoptosis and a novel iron-dependent cell death pathway termed ?ferroptosis?, the dysregulation of iron metabolism in human pathologies, and the use of iron chelators in cancer therapy. Twit Text FOAVip Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease ????Trends Biochem Sci http://www.kidney.de/pget.php?&tw=1&pmid=26725301 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26725301 #FOAvip English Wikipedia <ref>{{Cite pmid|26725301}}</ref> Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease #MMPMID26725301 Bogdan AR; Miyazawa M; Hashimoto K; Tsuji Y Trends Biochem Sci 2016[Mar]; 41 (3): 274-86 PMID26725301show ga Iron is necessary for life, but can also cause cell death. Accordingly, cells evolved a robust, tightly regulated suite of genes for maintaining iron homeostasis. Previous mechanistic studies on iron homeostasis have granted insight into the role of iron in human health and disease. We highlight new regulators of iron metabolism, including iron-trafficking proteins [solute carrier family 39, SLC39, also known as ZRT/IRT-like protein, ZIP; and poly-(rC)-binding protein, PCBP] and a cargo receptor (NCOA4) that is crucial for release of ferritin-bound iron. We also discuss emerging roles of iron in apoptosis and a novel iron-dependent cell death pathway termed ?ferroptosis?, the dysregulation of iron metabolism in human pathologies, and the use of iron chelators in cancer therapy. äRegulators of Iron Homeostasis: New Players in Metabolism, Cell Death,(epmc).pdf DeepDyve Pubget Overpricing