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10.1016/j.neuron.2009.09.032

http://scihub22266oqcxt.onion/10.1016/j.neuron.2009.09.032
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C4782919!4782919!19840546
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suck abstract from ncbi


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pmid19840546      Neuron 2009 ; 64 (1): 33-9
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  • The Stressed CNS: When Glucocorticoids Aggravate Inflammation #MMPMID19840546
  • Sorrells SF; Caso JR; Munhoz CD; Sapolsky RM
  • Neuron 2009[Oct]; 64 (1): 33-9 PMID19840546show ga
  • Glucocorticoids (GCs) are hormones released during the stress response that are well known for their immunosuppressive and anti-inflammatory properties; however, recent advances have uncovered situations wherein they have effects in the opposite direction. The CNS is a particularly interesting example, both because of its unique immune environment, and because GCs affect immune responses differently in different brain regions. In this perspective we discuss the contexts wherein GCs increase CNS inflammation and point out directions for future investigation.
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