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10.1186/s40168-016-0154-5 http://scihub22266oqcxt.onion/10.1186/s40168-016-0154-5 C4782286!4782286!26951112     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Microbiome 2016 ; 4 (ä): ä Nephropedia Template TP {{tp|p=26951112|t=2016. Recovering complete and draft population genomes from metagenome datasets |pdf=|usr=}}{{26951112}} gab.com Text Recovering complete and draft population genomes from metagenome datasets JO: Microbiome http://www.kidney.de/pget.php?&tw=1&pmid=26951112 #FOAvip Assembly of metagenomic sequence data into microbial genomes is of fundamental value to improving our understanding of microbial ecology and metabolism by elucidating the functional potential of hard-to-culture microorganisms. Here, we provide a synthesis of available methods to bin metagenomic contigs into species-level groups and highlight how genetic diversity, sequencing depth, and coverage influence binning success. Despite the computational cost on application to deeply sequenced complex metagenomes (e.g., soil), covarying patterns of contig coverage across multiple datasets significantly improves the binning process. We also discuss and compare current genome validation methods and reveal how these methods tackle the problem of chimeric genome bins i.e., sequences from multiple species. Finally, we explore how population genome assembly can be used to uncover biogeographic trends and to characterize the effect of in situ functional constraints on the genome-wide evolution. Twit Text FOAVip Recovering complete and draft population genomes from metagenome datasets ????Microbiome http://www.kidney.de/pget.php?&tw=1&pmid=26951112 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26951112 #FOAvip English Wikipedia <ref>{{Cite pmid|26951112}}</ref> Recovering complete and draft population genomes from metagenome datasets #MMPMID26951112 Sangwan N; Xia F; Gilbert JA Microbiome 2016[]; 4 (ä): ä PMID26951112show ga Assembly of metagenomic sequence data into microbial genomes is of fundamental value to improving our understanding of microbial ecology and metabolism by elucidating the functional potential of hard-to-culture microorganisms. Here, we provide a synthesis of available methods to bin metagenomic contigs into species-level groups and highlight how genetic diversity, sequencing depth, and coverage influence binning success. Despite the computational cost on application to deeply sequenced complex metagenomes (e.g., soil), covarying patterns of contig coverage across multiple datasets significantly improves the binning process. We also discuss and compare current genome validation methods and reveal how these methods tackle the problem of chimeric genome bins i.e., sequences from multiple species. Finally, we explore how population genome assembly can be used to uncover biogeographic trends and to characterize the effect of in situ functional constraints on the genome-wide evolution. äRecovering complete and draft population genomes from metagenome datas(epmc).pdf DeepDyve Pubget Overpricing