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10.1038/nrg3116 http://scihub22266oqcxt.onion/10.1038/nrg3116 C4782217!4782217!22179716     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Rev+Genet 2012 ; 13 (1): 14-20 Nephropedia Template TP {{tp|p=22179716|t=2012. Genomically humanised mice: technologies and promise |pdf=|usr=}}{{22179716}} gab.com Text Genomically humanised mice: technologies and promise JO: Nat Rev Genet http://www.kidney.de/pget.php?&tw=1&pmid=22179716 #FOAvip Mouse models have become an invaluable tool for understanding human health and disease owing to our ability to exquisitely manipulate the mouse genome. Recent progress in genomic analysis has led to an increase in the number and type of disease-causing mutations detected, and has also highlighted the importance of non-coding regions. As a result there is increasing interest in creating ?genomically? humanised mouse models, in which entire human genomic loci are transferred into the mouse genome. The technical challenges to achieving this aim are large but are starting to be tackled with success. Twit Text FOAVip Genomically humanised mice: technologies and promise ????Nat Rev Genet http://www.kidney.de/pget.php?&tw=1&pmid=22179716 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=22179716 #FOAvip English Wikipedia <ref>{{Cite pmid|22179716}}</ref> Genomically humanised mice: technologies and promise #MMPMID22179716 Devoy A; Bunton-Stasyshyn RK; Tybulewicz VL; Smith AJ; Fisher EM Nat Rev Genet 2012[Jan]; 13 (1): 14-20 PMID22179716show ga Mouse models have become an invaluable tool for understanding human health and disease owing to our ability to exquisitely manipulate the mouse genome. Recent progress in genomic analysis has led to an increase in the number and type of disease-causing mutations detected, and has also highlighted the importance of non-coding regions. As a result there is increasing interest in creating ?genomically? humanised mouse models, in which entire human genomic loci are transferred into the mouse genome. The technical challenges to achieving this aim are large but are starting to be tackled with success. äGenomically humanised mice: technologies and promise (epmc).pdf DeepDyve Pubget Overpricing