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10.1101/gad.275958.115

http://scihub22266oqcxt.onion/10.1101/gad.275958.115
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C4782050!4782050!26944681
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suck abstract from ncbi


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pmid26944681      Genes+Dev 2016 ; 30 (5): 567-78
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  • Visualizing allele-specific expression in single cells reveals epigenetic mosaicism in an H19 loss-of-imprinting mutant #MMPMID26944681
  • Ginart P; Kalish JM; Jiang CL; Yu AC; Bartolomei MS; Raj A
  • Genes Dev 2016[Mar]; 30 (5): 567-78 PMID26944681show ga
  • Imprinting defects can lead to inappropriate expression from the normally silenced allele, but it remains unclear whether every cell in a mutant organism follows the population average. Ginart et al. applied a new fluorescence in situ hybridization method that measures allele-specific expression in single cells to address this question in mutants exhibiting aberrant H19/Igf2 imprinting.
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