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10.1895/wormbook.1.24.1

http://scihub22266oqcxt.onion/10.1895/wormbook.1.24.1
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C4781631!4781631!18023121
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suck abstract from ncbi

pmid18023121      WormBook 2005 ; ä (ä): 1-17
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  • Complementation #MMPMID18023121
  • Yook K
  • WormBook 2005[]; ä (ä): 1-17 PMID18023121show ga
  • Mutations in many genes can result in a similar phenotype. Finding a number of mutants with the same phenotype tells you little about how many genes you are dealing with, and how mutable those genes are until you can assign those mutations to genetic loci. The genetic assay for gene assignment is called the complementation test. The simplicity and robustness of this test makes it a fundamental genetic tool for gene assignment. However, there are occasional unexpected outcomes from this test that bear explanation. This chapter reviews the complementation test and its various outcomes, highlighting relatively rare but nonetheless interesting exceptions such as intragenic complementation and non-allelic non-complementation.
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