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10.14740/jocmr2480w http://scihub22266oqcxt.onion/10.14740/jocmr2480w C4780491!4780491!26985248     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Clin+Med+Res 2016 ; 8 (4): 284-96 Nephropedia Template TP {{tp|p=26985248|t=2016. Signaling Pathways in Thyroid Cancer and Their Therapeutic Implications |pdf=|usr=}}{{26985248}} gab.com Text Signaling Pathways in Thyroid Cancer and Their Therapeutic Implications JO: J Clin Med Res http://www.kidney.de/pget.php?&tw=1&pmid=26985248 #FOAvip Thyroid cancer is a common malignancy of endocrine system, and has now become the fastest increasing cancer among all the malignancies. The development, progression, invasion, and metastasis are closely associated with multiple signaling pathways and the functions of related molecules, such as Src, Janus kinase (JAK)-signal transducers and activators of transcription (STAT), mitogen-activated protein kinase (MAPK), phosphoinositide 3-kinase (PI3K)/Akt, NF-?B, thyroid stimulating hormone receptor (TSHR), Wnt-?-catenin and Notch signaling pathways. Each of the signaling pathways could exert its function singly or through network with other pathways. These pathways could cooperate, promote, antagonize, or interact with each other to form a complex network for the regulation. Dysfunction of this network could increase the development, progression, invasion, and metastasis of thyroid cancer. Inoperable thyroid cancer still has a poor prognosis. However, signaling pathway-related targeted therapies offer the hope of longer quality of meaningful life for this small group of patients. Signaling pathway-related targets provide unprecedented opportunities for further research and clinical development of novel treatment strategies for this cancer. In the present work, the advances in these signaling pathways and targeted treatments of thyroid cancer were reviewed. Twit Text FOAVip Signaling Pathways in Thyroid Cancer and Their Therapeutic Implications ????J Clin Med Res http://www.kidney.de/pget.php?&tw=1&pmid=26985248 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26985248 #FOAvip English Wikipedia <ref>{{Cite pmid|26985248}}</ref> Signaling Pathways in Thyroid Cancer and Their Therapeutic Implications #MMPMID26985248 Jin S; Borkhuu O; Bao W; Yang YT J Clin Med Res 2016[Apr]; 8 (4): 284-96 PMID26985248show ga Thyroid cancer is a common malignancy of endocrine system, and has now become the fastest increasing cancer among all the malignancies. The development, progression, invasion, and metastasis are closely associated with multiple signaling pathways and the functions of related molecules, such as Src, Janus kinase (JAK)-signal transducers and activators of transcription (STAT), mitogen-activated protein kinase (MAPK), phosphoinositide 3-kinase (PI3K)/Akt, NF-?B, thyroid stimulating hormone receptor (TSHR), Wnt-?-catenin and Notch signaling pathways. Each of the signaling pathways could exert its function singly or through network with other pathways. These pathways could cooperate, promote, antagonize, or interact with each other to form a complex network for the regulation. Dysfunction of this network could increase the development, progression, invasion, and metastasis of thyroid cancer. Inoperable thyroid cancer still has a poor prognosis. However, signaling pathway-related targeted therapies offer the hope of longer quality of meaningful life for this small group of patients. Signaling pathway-related targets provide unprecedented opportunities for further research and clinical development of novel treatment strategies for this cancer. In the present work, the advances in these signaling pathways and targeted treatments of thyroid cancer were reviewed. äSignaling Pathways in Thyroid Cancer and Their Therapeutic Implication(epmc).pdf DeepDyve Pubget Overpricing