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10.5009/gnl15226 http://scihub22266oqcxt.onion/10.5009/gnl15226 C4780447!4780447!26934883     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Gut+Liver 2016 ; 10 (2): 166-76 Nephropedia Template TP {{tp|p=26934883|t=2016. The Role of Mesothelial Cells in Liver Development, Injury, and Regeneration |pdf=|usr=}}{{26934883}} gab.com Text The Role of Mesothelial Cells in Liver Development, Injury, and Regeneration JO: Gut Liver http://www.kidney.de/pget.php?&tw=1&pmid=26934883 #FOAvip Mesothelial cells (MCs) cover the surface of visceral organs and the parietal walls of cavities, and they synthesize lubricating fluids to create a slippery surface that facilitates movement between organs without friction. Recent studies have indicated that MCs play active roles in liver development, fibrosis, and regeneration. During liver development, the mesoderm produces MCs that form a single epithelial layer of the mesothelium. MCs exhibit an intermediate phenotype between epithelial cells and mesenchymal cells. Lineage tracing studies have indicated that during liver development, MCs act as mesenchymal progenitor cells that produce hepatic stellate cells, fibroblasts around blood vessels, and smooth muscle cells. Upon liver injury, MCs migrate inward from the liver surface and produce hepatic stellate cells or myofibroblast depending on the etiology, suggesting that MCs are the source of myofibroblasts in capsular fibrosis. Similar to the activation of hepatic stellate cells, transforming growth factor ? induces the conversion of MCs into myofibroblasts. Further elucidation of the biological and molecular changes involved in MC activation and fibrogenesis will contribute to the development of novel approaches for the prevention and therapy of liver fibrosis. Twit Text FOAVip The Role of Mesothelial Cells in Liver Development, Injury, and Regeneration ????Gut Liver http://www.kidney.de/pget.php?&tw=1&pmid=26934883 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26934883 #FOAvip English Wikipedia <ref>{{Cite pmid|26934883}}</ref> The Role of Mesothelial Cells in Liver Development, Injury, and Regeneration #MMPMID26934883 Lua I; Asahina K Gut Liver 2016[Mar]; 10 (2): 166-76 PMID26934883show ga Mesothelial cells (MCs) cover the surface of visceral organs and the parietal walls of cavities, and they synthesize lubricating fluids to create a slippery surface that facilitates movement between organs without friction. Recent studies have indicated that MCs play active roles in liver development, fibrosis, and regeneration. During liver development, the mesoderm produces MCs that form a single epithelial layer of the mesothelium. MCs exhibit an intermediate phenotype between epithelial cells and mesenchymal cells. Lineage tracing studies have indicated that during liver development, MCs act as mesenchymal progenitor cells that produce hepatic stellate cells, fibroblasts around blood vessels, and smooth muscle cells. Upon liver injury, MCs migrate inward from the liver surface and produce hepatic stellate cells or myofibroblast depending on the etiology, suggesting that MCs are the source of myofibroblasts in capsular fibrosis. Similar to the activation of hepatic stellate cells, transforming growth factor ? induces the conversion of MCs into myofibroblasts. Further elucidation of the biological and molecular changes involved in MC activation and fibrogenesis will contribute to the development of novel approaches for the prevention and therapy of liver fibrosis. äThe Role of Mesothelial Cells in Liver Development, Injury, and Regene(epmc).pdf DeepDyve Pubget Overpricing