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10.5487/TR.2016.32.1.009

http://scihub22266oqcxt.onion/10.5487/TR.2016.32.1.009
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C4780239!4780239!26977254
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suck abstract from ncbi


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pmid26977254      Toxicol+Res 2016 ; 32 (1): 9-14
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  • Advances in the Development and Validation of Test Methods in the United States #MMPMID26977254
  • Casey WM
  • Toxicol Res 2016[Jan]; 32 (1): 9-14 PMID26977254show ga
  • The National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) provides validation support for US Federal agencies and the US Tox21 interagency consortium, an interagency collaboration that is using high throughput screening (HTS) and other advanced approaches to better understand and predict chemical hazards to humans and the environment. The use of HTS data from assays relevant to the estrogen receptor signaling data pathway is used as an example of how HTS data can be combined with computational modeling to meet the needs of US agencies. As brief summary of US efforts in the areas of biologics testing, acute toxicity, and skin sensitization will also be provided.
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