Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26997959
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26997959
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Stem+Cells+Int
2016 ; 2016
(ä): 9352598
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Stem Cells for Bone Regeneration: From Cell-Based Therapies to Decellularised
Engineered Extracellular Matrices
#MMPMID26997959
Fisher JN
; Peretti GM
; Scotti C
Stem Cells Int
2016[]; 2016
(ä): 9352598
PMID26997959
show ga
Currently, autologous bone grafting represents the clinical gold standard in
orthopaedic surgery. In certain cases, however, alternative techniques are
required. The clinical utility of stem and stromal cells has been demonstrated
for the repair and regeneration of craniomaxillofacial and long bone defects
although clinical adoption of bone tissue engineering protocols has been very
limited. Initial tissue engineering studies focused on the bone marrow as a
source of cells for bone regeneration, and while a number of promising results
continue to emerge, limitations to this technique have prompted the exploration
of alternative cell sources, including adipose and muscle tissue. In this review
paper we discuss the advantages and disadvantages of cell sources with a focus on
adipose tissue and the bone marrow. Additionally, we highlight the relatively
recent paradigm of developmental engineering, which promotes the recapitulation
of naturally occurring developmental processes to allow the implant to optimally
respond to endogenous cues. Finally we examine efforts to apply lessons from
studies into different cell sources and developmental approaches to stimulate
bone growth by use of decellularised hypertrophic cartilage templates.