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10.1007/s12311-015-0676-6

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suck abstract from ncbi


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pmid26041073
      Cerebellum 2016 ; 15 (2 ): 159-64
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  • The Usefulness of the TOAST Classification and Prognostic Significance of Pyramidal Symptoms During the Acute Phase of Cerebellar Ischemic Stroke #MMPMID26041073
  • Dziadkowiak E ; Chojdak-?ukasiewicz J ; Guzi?ski M ; Noga L ; Paradowski B
  • Cerebellum 2016[Apr]; 15 (2 ): 159-64 PMID26041073 show ga
  • Cerebellar stroke is a rare condition with very nonspecific clinical features. The symptoms in the acute phase could imitate acute peripheral vestibular disorders or a brainstem lesion. The aim of this study was to assess the usefulness of the Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification in cerebellar stroke and the impact of clinical features on the prognosis. We retrospectively analyzed 107 patients with diagnosed ischemic cerebellar infarction. We studied the clinical features and compared them based on the location of the ischemic lesion and its distribution in the posterior interior cerebellar artery (PICA), superior cerebellar artery (SCA), and anterior inferior cerebellar artery (AICA) territories. According to the TOAST classification, stroke was more prevalent in atrial fibrillation (26/107) and when the lesion was in the PICA territory (39/107). Pyramidal signs occurred in 29/107 of patients and were more prevalent when the lesion was distributed in more than two vascular regions (p?=?0.00640). Mortality was higher among patients with ischemic lesion caused by cardiac sources (p?=?0.00094) and with pyramidal signs (p?=?0.00640). The TOAST classification is less useful in assessing supratentorial ischemic infarcts. Cardioembolic etiology, location of the ischemic lesion, and pyramidal signs support a negative prognosis.
  • |Adult [MESH]
  • |Aged [MESH]
  • |Aged, 80 and over [MESH]
  • |Arteries/*pathology [MESH]
  • |Cerebellar Diseases/*diagnosis/pathology [MESH]
  • |Diffusion Magnetic Resonance Imaging/methods [MESH]
  • |Female [MESH]
  • |Humans [MESH]
  • |Ischemia/*diagnosis/pathology [MESH]
  • |Male [MESH]
  • |Middle Aged [MESH]
  • |Prognosis [MESH]
  • |Retrospective Studies [MESH]
  • |Risk Factors [MESH]


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