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10.3748/wjg.v22.i9.2668 http://scihub22266oqcxt.onion/10.3748/wjg.v22.i9.2668 C4777991!4777991!26973407     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       World+J+Gastroenterol 2016 ; 22 (9): 2668-77 Nephropedia Template TP {{tp|p=26973407|t=2016. Epigenetic regulation of insulin-like growth factor axis in hepatocellular carcinoma |pdf=|usr=}}{{26973407}} gab.com Text Epigenetic regulation of insulin-like growth factor axis in hepatocellular carcinoma JO: World J Gastroenterol http://www.kidney.de/pget.php?&tw=1&pmid=26973407 #FOAvip The insulin-like growth factor (IGF) signaling pathway is an important pathway in the process of hepatocarcinogenesis, and the IGF network is clearly dysregulated in many cancers and developmental abnormalities. In hepatocellular carcinoma (HCC), only a minority of patients are eligible for curative treatments, such as tumor resection or liver transplant. Unfortunately, there is a high recurrence of HCC after surgical tumor removal. Recent research efforts have focused on targeting IGF axis members in an attempt to find therapeutic options for many health problems. In this review, we shed lights on the regulation of members of the IGF axis, mainly by microRNAs in HCC. MicroRNAs in HCC attempt to halt the aberrant expression of the IGF network, and a single microRNA can have multiple downstream targets in one or more signaling pathways. Targeting microRNAs is a relatively new approach for identifying an efficient radical cure for HCC. Twit Text FOAVip Epigenetic regulation of insulin-like growth factor axis in hepatocellular carcinoma ????World J Gastroenterol http://www.kidney.de/pget.php?&tw=1&pmid=26973407 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26973407 #FOAvip English Wikipedia <ref>{{Cite pmid|26973407}}</ref> Epigenetic regulation of insulin-like growth factor axis in hepatocellular carcinoma #MMPMID26973407 El Tayebi HM; Abdelaziz AI World J Gastroenterol 2016[Mar]; 22 (9): 2668-77 PMID26973407show ga The insulin-like growth factor (IGF) signaling pathway is an important pathway in the process of hepatocarcinogenesis, and the IGF network is clearly dysregulated in many cancers and developmental abnormalities. In hepatocellular carcinoma (HCC), only a minority of patients are eligible for curative treatments, such as tumor resection or liver transplant. Unfortunately, there is a high recurrence of HCC after surgical tumor removal. Recent research efforts have focused on targeting IGF axis members in an attempt to find therapeutic options for many health problems. In this review, we shed lights on the regulation of members of the IGF axis, mainly by microRNAs in HCC. MicroRNAs in HCC attempt to halt the aberrant expression of the IGF network, and a single microRNA can have multiple downstream targets in one or more signaling pathways. Targeting microRNAs is a relatively new approach for identifying an efficient radical cure for HCC. äEpigenetic regulation of insulin-like growth factor axis in hepatocell(epmc).pdf DeepDyve Pubget Overpricing