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10.5527/wjn.v5.i2.152 http://scihub22266oqcxt.onion/10.5527/wjn.v5.i2.152 C4777786!4777786!26981439     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       World+J+Nephrol 2016 ; 5 (2): 152-7 Nephropedia Template TP {{tp|p=26981439|t=2016. Proton-pump inhibitor-induced hypomagnesemia: Current research and proposed mechanisms |pdf=|usr=}}{{26981439}} gab.com Text Proton-pump inhibitor-induced hypomagnesemia: Current research and proposed mechanisms JO: World J Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=26981439 #FOAvip Since the early reports nearly a decade ago, proton-pump inhibitor-induced hypomagnesemia (PPIH) has become a well-recognized phenomenon. While many observational studies in the inpatient and outpatient populations have confirmed the association of PPI exposure and serum magnesium concentrations, there are no prospective, controlled studies to support causation. Molecular mechanisms of magnesium transporters, including the pH-dependent regulation of transient receptor potential melastatin-6 transporters in the colonic enterocyte, have been proposed to explain the effect of PPIs on magnesium reabsorption, but may be a small part of a more complicated interplay of molecular biology, pharmacology, and genetic predisposition. This review explores the current state of research in the field of PPIH and the proposed mechanisms of this effect. Twit Text FOAVip Proton-pump inhibitor-induced hypomagnesemia: Current research and proposed mechanisms ????World J Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=26981439 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26981439 #FOAvip English Wikipedia <ref>{{Cite pmid|26981439}}</ref> Proton-pump inhibitor-induced hypomagnesemia: Current research and proposed mechanisms #MMPMID26981439 William JH; Danziger J World J Nephrol 2016[Mar]; 5 (2): 152-7 PMID26981439show ga Since the early reports nearly a decade ago, proton-pump inhibitor-induced hypomagnesemia (PPIH) has become a well-recognized phenomenon. While many observational studies in the inpatient and outpatient populations have confirmed the association of PPI exposure and serum magnesium concentrations, there are no prospective, controlled studies to support causation. Molecular mechanisms of magnesium transporters, including the pH-dependent regulation of transient receptor potential melastatin-6 transporters in the colonic enterocyte, have been proposed to explain the effect of PPIs on magnesium reabsorption, but may be a small part of a more complicated interplay of molecular biology, pharmacology, and genetic predisposition. This review explores the current state of research in the field of PPIH and the proposed mechanisms of this effect. äProton-pump inhibitor-induced hypomagnesemia: Current research and pro(epmc).pdf DeepDyve Pubget Overpricing