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10.1093/biosci/biu058

http://scihub22266oqcxt.onion/10.1093/biosci/biu058
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suck abstract from ncbi


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pmid26955070      Bioscience 2014 ; 64 (6): 476-86
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  • Neurobiology of Caenorhabditis elegans Locomotion: Where Do We Stand? #MMPMID26955070
  • Gjorgjieva J; Biron D; Haspel G
  • Bioscience 2014[Jun]; 64 (6): 476-86 PMID26955070show ga
  • Animals use a nervous system for locomotion in some stage of their life cycle. The nematode Caenorhabditis elegans, a major animal model for almost all fields of experimental biology, has long been used for detailed studies of genetic and physiological locomotion mechanisms. Of its 959 somatic cells, 302 are neurons that are identifiable by lineage, location, morphology, and neurochemistry in every adult hermaphrodite. Of those, 75 motoneurons innervate body wall muscles that provide the thrust during locomotion. In this Overview, we concentrate on the generation of either forward- or backward-directed motion during crawling and swimming. We describe locomotion behavior, the parts constituting the locomotion system, and the relevant neuronal connectivity. Because it is not yet fully understood how these components combine to generate locomotion, we discuss competing hypotheses and models.
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