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10.12688/f1000research.7210.1

http://scihub22266oqcxt.onion/10.12688/f1000research.7210.1
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C4776671!4776671!26973786
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suck abstract from ncbi

pmid26973786      F1000Res 2016 ; 5 (ä): ä
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  • Tumour Cell Heterogeneity #MMPMID26973786
  • Gay L; Baker AM; Graham TA
  • F1000Res 2016[]; 5 (ä): ä PMID26973786show ga
  • The population of cells that make up a cancer are manifestly heterogeneous at the genetic, epigenetic, and phenotypic levels. In this mini-review, we summarise the extent of intra-tumour heterogeneity (ITH) across human malignancies, review the mechanisms that are responsible for generating and maintaining ITH, and discuss the ramifications and opportunities that ITH presents for cancer prognostication and treatment.
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