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10.1073/pnas.1600511113 http://scihub22266oqcxt.onion/10.1073/pnas.1600511113 C4776516!4776516!26858454     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2016 ; 113 (8): 2218-22 Nephropedia Template TP {{tp|p=26858454|t=2016. High Elmo1 expression aggravates and low Elmo1 expression prevents diabetic nephropathy |pdf=|usr=}}{{26858454}} gab.com Text High Elmo1 expression aggravates and low Elmo1 expression prevents diabetic nephropathy JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=26858454 #FOAvip About one-third of patients with type 1 diabetes mellitus develop nephropathy, which often progresses to end-stage renal diseases. The present study demonstrates that below-normal Elmo1 expression in mice ameliorates the albuminuria and glomerular histological changes resulting from long-standing type 1 diabetes, whereas above-normal Elmo1 expression makes both worse. Increasing Elmo1 expression leads to aggravation of oxidative stress markers and enhances the expression of fibrogenic genes. Suppressing Elmo1 action in human patients could be a promising option for treating/preventing the progressive deterioration of renal function in diabetes. Twit Text FOAVip High Elmo1 expression aggravates and low Elmo1 expression prevents diabetic nephropathy ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=26858454 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26858454 #FOAvip English Wikipedia <ref>{{Cite pmid|26858454}}</ref> High Elmo1 expression aggravates and low Elmo1 expression prevents diabetic nephropathy #MMPMID26858454 Hathaway CK; Chang AS; Grant R; Kim HS; Madden VJ; Bagnell CR; Jennette JC; Smithies O; Kakoki M Proc Natl Acad Sci U S A 2016[Feb]; 113 (8): 2218-22 PMID26858454show ga About one-third of patients with type 1 diabetes mellitus develop nephropathy, which often progresses to end-stage renal diseases. The present study demonstrates that below-normal Elmo1 expression in mice ameliorates the albuminuria and glomerular histological changes resulting from long-standing type 1 diabetes, whereas above-normal Elmo1 expression makes both worse. Increasing Elmo1 expression leads to aggravation of oxidative stress markers and enhances the expression of fibrogenic genes. Suppressing Elmo1 action in human patients could be a promising option for treating/preventing the progressive deterioration of renal function in diabetes. äHigh Elmo1 expression aggravates and low Elmo1 expression prevents dia(epmc).pdf DeepDyve Pubget Overpricing