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10.1016/j.it.2016.01.001 http://scihub22266oqcxt.onion/10.1016/j.it.2016.01.001 C4775298!4775298!26830540     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Trends+Immunol 2016 ; 37 (3): 170-80 Nephropedia Template TP {{tp|p=26830540|t=2016. T cell Vaccinology: Beyond the Reflection of Infectious Responses |pdf=|usr=}}{{26830540}} gab.com Text T cell Vaccinology: Beyond the Reflection of Infectious Responses JO: Trends Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26830540 #FOAvip Inducing sustained, robust CD8+ T cell responses is necessary for therapeutic intervention in chronic infectious diseases and cancer. Unfortunately, most adjuvant formulations fail to induce substantial cellular immunity in humans. Attenuated acute infectious agents induce strong CD8+ T cell immunity, and are thought to therefore represent a good road map for guiding the development of subunit vaccines capable of inducing the same. However, recent evidence suggests that this assumption may need reconsideration. Here we provide an overview of subunit vaccine history as it pertains to instigating T cell responses. We argue that in light of evidence demonstrating that T cell responses to vaccination differ from those induced by infectious challenge, research in pursuit of cellular immunity-inducing vaccine adjuvants should no longer follow only the infection paradigm. Twit Text FOAVip T cell Vaccinology: Beyond the Reflection of Infectious Responses ????Trends Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26830540 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26830540 #FOAvip English Wikipedia <ref>{{Cite pmid|26830540}}</ref> T cell Vaccinology: Beyond the Reflection of Infectious Responses #MMPMID26830540 Pennock ND; Kedl JD; Kedl RM Trends Immunol 2016[Mar]; 37 (3): 170-80 PMID26830540show ga Inducing sustained, robust CD8+ T cell responses is necessary for therapeutic intervention in chronic infectious diseases and cancer. Unfortunately, most adjuvant formulations fail to induce substantial cellular immunity in humans. Attenuated acute infectious agents induce strong CD8+ T cell immunity, and are thought to therefore represent a good road map for guiding the development of subunit vaccines capable of inducing the same. However, recent evidence suggests that this assumption may need reconsideration. Here we provide an overview of subunit vaccine history as it pertains to instigating T cell responses. We argue that in light of evidence demonstrating that T cell responses to vaccination differ from those induced by infectious challenge, research in pursuit of cellular immunity-inducing vaccine adjuvants should no longer follow only the infection paradigm. äT cell Vaccinology: Beyond the Reflection of Infectious Responses (epmc).pdf DeepDyve Pubget Overpricing