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10.3892/br.2016.574 http://scihub22266oqcxt.onion/10.3892/br.2016.574 C4774316!4774316!26998265     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biomed+Rep 2016 ; 4 (3): 293-9 Nephropedia Template TP {{tp|p=26998265|t=2016. Role of several histone lysine methyltransferases in tumor development |pdf=|usr=}}{{26998265}} gab.com Text Role of several histone lysine methyltransferases in tumor development JO: Biomed Rep http://www.kidney.de/pget.php?&tw=1&pmid=26998265 #FOAvip The field of cancer epigenetics has been evolving rapidly in recent decades. Epigenetic mechanisms include DNA methylation, histone modifications and microRNAs. Histone modifications are important markers of function and chromatin state. Aberrant histone methylation frequently occurs in tumor development and progression. Multiple studies have identified that histone lysine methyltransferases regulate gene transcription through the methylation of histone, which affects cell proliferation and differentiation, cell migration and invasion, and other biological characteristics. Histones have variant lysine sites for different levels of methylation, catalyzed by different lysine methyltransferases, which have numerous effects on human cancers. The present review focused on the most recent advances, described the key function sites of histone lysine methyltransferases, integrated significant quantities of data to introduce several compelling histone lysine methyltransferases in various types of human cancers, summarized their role in tumor development and discussed their potential mechanisms of action. Twit Text FOAVip Role of several histone lysine methyltransferases in tumor development ????Biomed Rep http://www.kidney.de/pget.php?&tw=1&pmid=26998265 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26998265 #FOAvip English Wikipedia <ref>{{Cite pmid|26998265}}</ref> Role of several histone lysine methyltransferases in tumor development #MMPMID26998265 LI J; ZHU S; KE XX; CUI H Biomed Rep 2016[Mar]; 4 (3): 293-9 PMID26998265show ga The field of cancer epigenetics has been evolving rapidly in recent decades. Epigenetic mechanisms include DNA methylation, histone modifications and microRNAs. Histone modifications are important markers of function and chromatin state. Aberrant histone methylation frequently occurs in tumor development and progression. Multiple studies have identified that histone lysine methyltransferases regulate gene transcription through the methylation of histone, which affects cell proliferation and differentiation, cell migration and invasion, and other biological characteristics. Histones have variant lysine sites for different levels of methylation, catalyzed by different lysine methyltransferases, which have numerous effects on human cancers. The present review focused on the most recent advances, described the key function sites of histone lysine methyltransferases, integrated significant quantities of data to introduce several compelling histone lysine methyltransferases in various types of human cancers, summarized their role in tumor development and discussed their potential mechanisms of action. äRole of several histone lysine methyltransferases in tumor development(epmc).pdf DeepDyve Pubget Overpricing