Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.3892/br.2016.590 http://scihub22266oqcxt.onion/10.3892/br.2016.590 C4774312!4774312!26998260     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biomed+Rep 2016 ; 4 (3): 259-62 Nephropedia Template TP {{tp|p=26998260|t=2016. Mitochondrial DNA heteroplasmy in human health and disease |pdf=|usr=}}{{26998260}} gab.com Text Mitochondrial DNA heteroplasmy in human health and disease JO: Biomed Rep http://www.kidney.de/pget.php?&tw=1&pmid=26998260 #FOAvip The biomedical literature has extensively documented the functional roles of genetic polymorphisms in concert with well-characterized somatic mutations in the etiology and progression of major metastatic diseases afflicting human populations. Mitochondrial heteroplasmy exists as a dynamically determined co-expression of inherited polymorphisms and somatic mutations in varying ratios within individual mitochondrial DNA genomes with repetitive patterns of tissue specificity. Mechanistically, carcinogenic cellular processes include profound alterations of normative mitochondrial function, notably dependence on aerobic and anaerobic glycolysis, and aberrant production and release of lactate, according to a classic theory. Within the translational context of human health and disease, the present review discusses the necessity of establishing critical foci designed to probe multiple biological roles of mitochondrial heteroplasmy in cancer biology. Twit Text FOAVip Mitochondrial DNA heteroplasmy in human health and disease ????Biomed Rep http://www.kidney.de/pget.php?&tw=1&pmid=26998260 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26998260 #FOAvip English Wikipedia <ref>{{Cite pmid|26998260}}</ref> Mitochondrial DNA heteroplasmy in human health and disease #MMPMID26998260 STEFANO GB; KREAM RM Biomed Rep 2016[Mar]; 4 (3): 259-62 PMID26998260show ga The biomedical literature has extensively documented the functional roles of genetic polymorphisms in concert with well-characterized somatic mutations in the etiology and progression of major metastatic diseases afflicting human populations. Mitochondrial heteroplasmy exists as a dynamically determined co-expression of inherited polymorphisms and somatic mutations in varying ratios within individual mitochondrial DNA genomes with repetitive patterns of tissue specificity. Mechanistically, carcinogenic cellular processes include profound alterations of normative mitochondrial function, notably dependence on aerobic and anaerobic glycolysis, and aberrant production and release of lactate, according to a classic theory. Within the translational context of human health and disease, the present review discusses the necessity of establishing critical foci designed to probe multiple biological roles of mitochondrial heteroplasmy in cancer biology. äMitochondrial DNA heteroplasmy in human health and disease (epmc).pdf DeepDyve Pubget Overpricing