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10.1016/bs.ctm.2015.07.001 http://scihub22266oqcxt.onion/10.1016/bs.ctm.2015.07.001 C4772872!4772872!26610918     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Top+Membr 2015 ; 76 (ä): 305-36 Nephropedia Template TP {{tp|p=26610918|t=2015. Building from the ground up: basement membranes in Drosophila development |pdf=|usr=}}{{26610918}} gab.com Text Building from the ground up: basement membranes in Drosophila development JO: Curr Top Membr http://www.kidney.de/pget.php?&tw=1&pmid=26610918 #FOAvip Basement Membranes (BMs) are sheet-like extracellular matrices found at the basal surfaces of epithelial tissues. The structural and functional diversity of these matrices within the body endows them with the ability to affect multiple aspects of cell behavior and communication; for this reason, BMs are integral to many developmental processes. The power of Drosophila genetics, as applied to the BM, has yielded substantial insight into how these matrices influence development. Here, we explore three facets of BM biology to which Drosophila research has made particularly important contributions. First we discuss how newly synthesized BM proteins are secreted to and assembled exclusively on basal epithelial surfaces. Next, we examine how regulation of the structural properties of the BM mechanically supports and guides tissue morphogenesis. Finally, we explore how BMs influence development through the modulation of several major signaling pathways. Twit Text FOAVip Building from the ground up: basement membranes in Drosophila development ????Curr Top Membr http://www.kidney.de/pget.php?&tw=1&pmid=26610918 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26610918 #FOAvip English Wikipedia <ref>{{Cite pmid|26610918}}</ref> Building from the ground up: basement membranes in Drosophila development #MMPMID26610918 Isabella AJ; Horne-Badovinac S Curr Top Membr 2015[]; 76 (ä): 305-36 PMID26610918show ga Basement Membranes (BMs) are sheet-like extracellular matrices found at the basal surfaces of epithelial tissues. The structural and functional diversity of these matrices within the body endows them with the ability to affect multiple aspects of cell behavior and communication; for this reason, BMs are integral to many developmental processes. The power of Drosophila genetics, as applied to the BM, has yielded substantial insight into how these matrices influence development. Here, we explore three facets of BM biology to which Drosophila research has made particularly important contributions. First we discuss how newly synthesized BM proteins are secreted to and assembled exclusively on basal epithelial surfaces. Next, we examine how regulation of the structural properties of the BM mechanically supports and guides tissue morphogenesis. Finally, we explore how BMs influence development through the modulation of several major signaling pathways. äBuilding from the ground up: basement membranes in Drosophila developm(epmc).pdf DeepDyve Pubget Overpricing