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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Global+Spine+J
2016 ; 6
(2
): 195-204
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English Wikipedia
Ossification of the Posterior Longitudinal Ligament: Etiology, Diagnosis, and
Outcomes of Nonoperative and Operative Management
#MMPMID26933622
Abiola R
; Rubery P
; Mesfin A
Global Spine J
2016[Mar]; 6
(2
): 195-204
PMID26933622
show ga
Study Design?Narrative review. Objective?To provide an overview on the diagnosis,
natural history, and nonoperative and operative management of ossification of the
posterior longitudinal ligament (OPLL). OPLL is a multifactorial condition caused
by ectopic hyperostosis and calcification of the posterior longitudinal ligament.
Familial inheritance and genetic factors have been implicated in the etiology of
OPLL. The cervical spine is most commonly affected followed by the thoracic
spine. The clinical manifestations range from asymptomatic to myelopathy or
myeloradiculopathy. Methods?Using PubMed, studies published prior to October 2014
with the keywords "OPLL, etiology"; "OPLL, genetics"; "OPLL, spinal cord injury";
"OPLL, natural history"; "OPLL, non-surgical management"; OPLL, surgical
management"; "OPLL, surgical complications" were evaluated. Results?The review
addresses the etiology, epidemiology, classification, clinical presentation,
imaging findings, and nonoperative and operative management of OPLL.
Complications associated with surgical management of OPLL are also discussed.
Conclusions?OPLL commonly presents with myelopathy and radiculopathy. Spine
providers should consider OPLL in their differential diagnosis and when reviewing
images. If surgical intervention is pursued, imaging-based measurements and
findings can help in choosing an anterior versus posterior surgical approach.
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