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http://scihub22266oqcxt.onion/ C4770720!4770720!26462024     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncotarget 2015 ; 6 (36): 38552-65 Nephropedia Template TP {{tp|p=26462024|t=2015. Chromosomal instability triggers cell death via local signalling through the innate immune receptor Toll |pdf=|usr=}}{{26462024}} gab.com Text Chromosomal instability triggers cell death via local signalling through the innate immune receptor Toll JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=26462024 #FOAvip Chromosomal instability (CIN) is a hallmark of cancer and has been implicated in cancer initiation, progression and the development of resistance to traditional cancer therapy. Here we identify a new property of CIN cells, showing that inducing CIN in proliferating Drosophila larval tissue leads to the activation of innate immune signalling in CIN cells. Manipulation of this immune pathway strongly affects the survival of CIN cells, primarily via JNK, which responds to both Toll and TNF?/Eiger. This pathway also activates Mmp1, which recruits hemocytes to the CIN tissue to provide local amplification of the immune response that is needed for effective elimination of CIN cells. Twit Text FOAVip Chromosomal instability triggers cell death via local signalling through the innate immune receptor Toll ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=26462024 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26462024 #FOAvip English Wikipedia <ref>{{Cite pmid|26462024}}</ref> Chromosomal instability triggers cell death via local signalling through the innate immune receptor Toll #MMPMID26462024 Liu D; Shaukat Z; Saint RB; Gregory SL Oncotarget 2015[Nov]; 6 (36): 38552-65 PMID26462024show ga Chromosomal instability (CIN) is a hallmark of cancer and has been implicated in cancer initiation, progression and the development of resistance to traditional cancer therapy. Here we identify a new property of CIN cells, showing that inducing CIN in proliferating Drosophila larval tissue leads to the activation of innate immune signalling in CIN cells. Manipulation of this immune pathway strongly affects the survival of CIN cells, primarily via JNK, which responds to both Toll and TNF?/Eiger. This pathway also activates Mmp1, which recruits hemocytes to the CIN tissue to provide local amplification of the immune response that is needed for effective elimination of CIN cells. äChromosomal instability triggers cell death via local signalling throu(epmc).pdf DeepDyve Pubget Overpricing