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10.1155/2016/1549063

http://scihub22266oqcxt.onion/10.1155/2016/1549063
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C4770136!4770136!26980923
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suck abstract from ncbi


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pmid26980923      Dis+Markers 2016 ; 2016 (ä): ä
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  • Serum Galectin and Renal Dysfunction in ST-Segment Elevation Myocardial Infarction #MMPMID26980923
  • Karetnikova V; Osokina A; Gruzdeva O; Uchasova E; Zykov M; Kalaeva V; Kashtalap V; Shafranskaya K; Hryachkova O; Barbarash O
  • Dis Markers 2016[]; 2016 (ä): ä PMID26980923show ga
  • This study aimed to evaluate the association between serum galectin levels and renal dysfunction in relation to in-hospital prognosis and unfavorable prognosis 1 year after ST-elevated myocardial infarction (STEMI). Patients were assigned to two groups according to the cystatin C-based estimate of GFR on day 12 after STEMI: (1) STEMI patients with normal renal function (GFR based on cystatin C levels = 60?mL/min/1.73?m2) and (2) those with renal dysfunction (RD) (GFR based on cystatin C levels <60?mL/min/1.73?m2). A decrease in GFR estimated from the CKD-EPI equation on day 12 was more frequently found in patients with a reduced GFR based on cystatin C levels (41.9%) compared with those without RD (21.3%). Galectin levels exceeded the cut-off value (17.8?ng/mL) in 50.6% of cases in the group with GFR <60?mL/min/1.73?m2 and in 32% of cases in the group with a normal GFR. The presence of RD and elevated galectin levels >17.8?ng/mL on day 12 after MI are independent predictors of an adverse prognosis at 1 year in STEMI patients. Elevated galectin levels are directly correlated with the presence of early postinfarction angina.
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