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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Am+Soc+Nephrol
2016 ; 27
(3
): 687-97
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Progression after AKI: Understanding Maladaptive Repair Processes to Predict and
Identify Therapeutic Treatments
#MMPMID26519085
Basile DP
; Bonventre JV
; Mehta R
; Nangaku M
; Unwin R
; Rosner MH
; Kellum JA
; Ronco C
J Am Soc Nephrol
2016[Mar]; 27
(3
): 687-97
PMID26519085
show ga
Recent clinical studies indicate a strong link between AKI and progression of
CKD. The increasing prevalence of AKI must compel the nephrology community to
consider the long-term ramifications of this syndrome. Considerable gaps in
knowledge exist regarding the connection between AKI and CKD. The 13th Acute
Dialysis Quality Initiative meeting entitled "Therapeutic Targets of Human Acute
Kidney Injury: Harmonizing Human and Experimental Animal Acute Kidney Injury"
convened in April of 2014 and assigned a working group to focus on issues related
to progression after AKI. This article provides a summary of the key conclusions
and recommendations of the group, including an emphasis on terminology related to
injury and repair processes for both clinical and preclinical studies,
elucidation of pathophysiologic alterations of AKI, identification of potential
treatment strategies, identification of patients predisposed to progression, and
potential management strategies.