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10.1002/iid3.94 http://scihub22266oqcxt.onion/10.1002/iid3.94 C4768064!4768064!27042302     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27042302.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Immun+Inflamm+Dis 2016 ; 4 (1): 64-9 Nephropedia Template TP {{tp|p=27042302|t=2016. Prostaglandin D2 metabolites as a biomarker of in vivo mast cell activation in systemic mastocytosis and rheumatoid arthritis |pdf=|usr=}}{{27042302}} gab.com Text Prostaglandin D2 metabolites as a biomarker of in vivo mast cell activation in systemic mastocytosis and rheumatoid arthritis JO: Immun Inflamm Dis http://www.kidney.de/pget.php?&tw=1&pmid=27042302 #FOAvip Mast cells (MCs) participate in diseases such as systemic mastocytosis (SM) and allergic conditions. Less well understood is the role of MCs in non?allergic inflammatory disorders like rheumatoid arthritis (RA). Studying definitive roles for MCs in human diseases has been hampered by the lack of a well?accepted biomarker for monitoring in vivo MC activation. This study aimed to investigate the utility of urinary tetranor PGDM (T?PGDM) as a biomarker of in vivo MC activation in patients with SM, and apply this biomarker to assess MC involvement in relation to RA disease activity. A prospective, cross?sectional cohort study was conducted to measure a major urinary metabolite of prostaglandin D2, T?PGDM. Urine samples were collected from patients with RA (n?=?60), SM (n?=?17) and healthy normal controls (n?=?16) and T?PGDM excretion was determined by enzyme immunoassay as nanograms per milligram of urinary creatinine (ng/mg Cr). Mean urinary T?PGDM excretion was significantly higher (p?<?0.01) in patients with SM compared to controls (37.2 vs. 11.5?ng/mg Cr) with 65% of SM patients showing elevated levels. One third of patients with RA had elevated T?PGDM excretion, and the mean level in the RA group (20.0?ng/mg Cr) was significantly higher than controls (p?<?0.01). Medications inhibiting cyclooxygenase reduced T?PGDM excretion. Urinary T?PGDM excretion appears promising as a biomarker of in vivo MC activity and elevated levels in 33% of patients with RA provides evidence of MC activation in this disease. Twit Text FOAVip Prostaglandin D2 metabolites as a biomarker of in vivo mast cell activation in systemic mastocytosis and rheumatoid arthritis ????Immun Inflamm Dis http://www.kidney.de/pget.php?&tw=1&pmid=27042302 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27042302 #FOAvip English Wikipedia <ref>{{Cite pmid|27042302}}</ref> Prostaglandin D2 metabolites as a biomarker of in vivo mast cell activation in systemic mastocytosis and rheumatoid arthritis #MMPMID27042302 Cho C; Nguyen A; Bryant KJ; O'Neill SG; McNeil HP Immun Inflamm Dis 2016[Mar]; 4 (1): 64-9 PMID27042302show ga Mast cells (MCs) participate in diseases such as systemic mastocytosis (SM) and allergic conditions. Less well understood is the role of MCs in non?allergic inflammatory disorders like rheumatoid arthritis (RA). Studying definitive roles for MCs in human diseases has been hampered by the lack of a well?accepted biomarker for monitoring in vivo MC activation. This study aimed to investigate the utility of urinary tetranor PGDM (T?PGDM) as a biomarker of in vivo MC activation in patients with SM, and apply this biomarker to assess MC involvement in relation to RA disease activity. A prospective, cross?sectional cohort study was conducted to measure a major urinary metabolite of prostaglandin D2, T?PGDM. Urine samples were collected from patients with RA (n?=?60), SM (n?=?17) and healthy normal controls (n?=?16) and T?PGDM excretion was determined by enzyme immunoassay as nanograms per milligram of urinary creatinine (ng/mg Cr). Mean urinary T?PGDM excretion was significantly higher (p? äProstaglandin D2 metabolites as a biomarker of in vivo mast cell activ(epmc).pdf DeepDyve Pubget Overpricing