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10.1172/JCI83083 http://scihub22266oqcxt.onion/10.1172/JCI83083 C4767335!4767335!26928035     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Clin+Invest ä ; 126 (3): 821-8 Nephropedia Template TP {{tp|p=26928035|t=ä. Endothelial fluid shear stress sensing in vascular health and disease |pdf=|usr=}}{{26928035}} gab.com Text Endothelial fluid shear stress sensing in vascular health and disease JO: J Clin Invest http://www.kidney.de/pget.php?&tw=1&pmid=26928035 #FOAvip Endothelial cells transduce the frictional force from blood flow (fluid shear stress) into biochemical signals that regulate gene expression and cell behavior via specialized mechanisms and pathways. These pathways shape the vascular system during development and during postnatal and adult life to optimize flow to tissues. The same pathways also contribute to atherosclerosis and vascular malformations. This Review covers recent advances in basic mechanisms of flow signaling and the involvement of these mechanisms in vascular physiology, remodeling, and these diseases. We propose that flow sensing pathways that govern normal morphogenesis can contribute to disease under pathological conditions or can be altered to induce disease. Viewing atherosclerosis and vascular malformations as instances of pathological morphogenesis provides a unifying perspective that may aid in developing new therapies. Twit Text FOAVip Endothelial fluid shear stress sensing in vascular health and disease ????J Clin Invest http://www.kidney.de/pget.php?&tw=1&pmid=26928035 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26928035 #FOAvip English Wikipedia <ref>{{Cite pmid|26928035}}</ref> Endothelial fluid shear stress sensing in vascular health and disease #MMPMID26928035 Baeyens N; Bandyopadhyay C; Coon BG; Yun S; Schwartz MA J Clin Invest ä[]; 126 (3): 821-8 PMID26928035show ga Endothelial cells transduce the frictional force from blood flow (fluid shear stress) into biochemical signals that regulate gene expression and cell behavior via specialized mechanisms and pathways. These pathways shape the vascular system during development and during postnatal and adult life to optimize flow to tissues. The same pathways also contribute to atherosclerosis and vascular malformations. This Review covers recent advances in basic mechanisms of flow signaling and the involvement of these mechanisms in vascular physiology, remodeling, and these diseases. We propose that flow sensing pathways that govern normal morphogenesis can contribute to disease under pathological conditions or can be altered to induce disease. Viewing atherosclerosis and vascular malformations as instances of pathological morphogenesis provides a unifying perspective that may aid in developing new therapies. äEndothelial fluid shear stress sensing in vascular health and disease (epmc).pdf DeepDyve Pubget Overpricing