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10.1111/bcp.12720 http://scihub22266oqcxt.onion/10.1111/bcp.12720 C4767205!4767205!26174744     free     free     free       Br+J+Clin+Pharmacol 2016 ; 81 (3): 412-9 Nephropedia Template TP {{tp|p=26174744|t=2016. Treatment of drug?induced seizures |pdf=|usr=}}{{26174744}} gab.com Text Treatment of drug induced seizures JO: Br J Clin Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=26174744 #FOAvip Seizures are a common complication of drug intoxication, and up to 9% of status epilepticus cases are caused by a drug or poison. While the specific drugs associated with drug?induced seizures may vary by geography and change over time, common reported causes include antidepressants, stimulants and antihistamines. Seizures occur generally as a result of inadequate inhibitory influences (e.g., gamma aminobutyric acid, GABA) or excessive excitatory stimulation (e.g. glutamate) although many other neurotransmitters play a role. Most drug?induced seizures are self?limited. However, status epilepticus occurs in up to 10% of cases. Prolonged or recurrent seizures can lead to serious complications and require vigorous supportive care and anticonvulsant drugs. Benzodiazepines are generally accepted as the first line anticonvulsant therapy for drug?induced seizures. If benzodiazepines fail to halt seizures promptly, second line drugs include barbiturates and propofol. If isoniazid poisoning is a possibility, pyridoxine is given. Continuous infusion of one or more anticonvulsants may be required in refractory status epilepticus. There is no role for phenytoin in the treatment of drug?induced seizures. The potential role of ketamine and levetiracetam is promising but not established. Twit Text FOAVip Treatment of drug induced seizures ????Br J Clin Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=26174744 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26174744 #FOAvip English Wikipedia <ref>{{Cite pmid|26174744}}</ref> Treatment of drug?induced seizures #MMPMID26174744 Chen H; Albertson TE; Olson KR Br J Clin Pharmacol 2016[Mar]; 81 (3): 412-9 PMID26174744show ga Seizures are a common complication of drug intoxication, and up to 9% of status epilepticus cases are caused by a drug or poison. While the specific drugs associated with drug?induced seizures may vary by geography and change over time, common reported causes include antidepressants, stimulants and antihistamines. Seizures occur generally as a result of inadequate inhibitory influences (e.g., gamma aminobutyric acid, GABA) or excessive excitatory stimulation (e.g. glutamate) although many other neurotransmitters play a role. Most drug?induced seizures are self?limited. However, status epilepticus occurs in up to 10% of cases. Prolonged or recurrent seizures can lead to serious complications and require vigorous supportive care and anticonvulsant drugs. Benzodiazepines are generally accepted as the first line anticonvulsant therapy for drug?induced seizures. If benzodiazepines fail to halt seizures promptly, second line drugs include barbiturates and propofol. If isoniazid poisoning is a possibility, pyridoxine is given. Continuous infusion of one or more anticonvulsants may be required in refractory status epilepticus. There is no role for phenytoin in the treatment of drug?induced seizures. The potential role of ketamine and levetiracetam is promising but not established. äTreatment of drug?induced seizures (epmc).pdf DeepDyve Pubget Overpricing