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10.1111/bcp.12736 http://scihub22266oqcxt.onion/10.1111/bcp.12736 C4767197!4767197 !26255881     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26255881 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Br+J+Clin+Pharmacol 2016 ; 81 (3 ): 437-45 Nephropedia Template TP {{tp|p=26255881 |t=2016. Antidotes to coumarins, isoniazid, methotrexate and thyroxine, toxins that work via metabolic processes |pdf=|usr=}}{{26255881 }} gab.com Text Antidotes to coumarins, isoniazid, methotrexate and thyroxine, toxins that work via metabolic processes JO: Br J Clin Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=26255881 #FOAvip Some toxins cause their effects by affecting physiological processes that are fundamental to cell function or cause systemic effects as a result of cellular interaction. This review focuses on four examples, coumarin anticoagulants, isoniazid, methotrexate and thyroxine from the context of management of overdose as seen in acute general hospitals. The current basic clinical pharmacology of the toxin, the clinical features in overdose and evidence base for specific antidotes are discussed. The treatment for this group is based on an understanding of the toxic mechanism, but studies to determine the optimum dose of antidote are still required in all these toxins except thyroxine, where treatment dose is based on symptoms resulting from the overdose. Twit Text FOAVip Antidotes to coumarins, isoniazid, methotrexate and thyroxine, toxins that work via metabolic processes ????Br J Clin Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=26255881 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26255881 #FOAvip English Wikipedia <ref>{{Cite pmid|26255881 }}</ref> Antidotes to coumarins, isoniazid, methotrexate and thyroxine, toxins that work via metabolic processes #MMPMID26255881 Bateman DN ; Page CB Br J Clin Pharmacol 2016[Mar]; 81 (3 ): 437-45 PMID26255881 show ga Some toxins cause their effects by affecting physiological processes that are fundamental to cell function or cause systemic effects as a result of cellular interaction. This review focuses on four examples, coumarin anticoagulants, isoniazid, methotrexate and thyroxine from the context of management of overdose as seen in acute general hospitals. The current basic clinical pharmacology of the toxin, the clinical features in overdose and evidence base for specific antidotes are discussed. The treatment for this group is based on an understanding of the toxic mechanism, but studies to determine the optimum dose of antidote are still required in all these toxins except thyroxine, where treatment dose is based on symptoms resulting from the overdose. |Antidotes/*therapeutic use [MESH] |Coumarins/metabolism/*poisoning [MESH] |Disease Management [MESH] |Drug Overdose/*drug therapy/*metabolism/prevention & control [MESH] |Humans [MESH] |Isoniazid/metabolism/*poisoning [MESH] |Methotrexate/metabolism/*poisoning [MESH]Antidotes to coumarins, isoniazid, methotrexate and thyroxine, toxins (epmc).pdf DeepDyve Pubget Overpricing